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With the rapid development of autonomous and intelligent devices driven by soft actuators, ion soft actuators in flexible intelligent devices have several advantages over other actuators, including their light weight, low voltage drive, large strain, good flexibility, fast response, etc. Traditional ionic polymer metal composites have received a lot of attention over the past decades, but they suffer...
Combinational Photothermal‐Immunotherapy
In article number 2206441, Longjiang Zhang, Peng Huang, Zhongqiu Wang, and co‐workers load dual‐immune inhibitors nanomodulators for combinational photothermal‐immunotherapy through regulating abnormal enzymatic metabolism of IDO, blocking PD‐L1/PD‐1 and CD47/SIRPα to reverse immunosuppressive tumor microenvironment, and prevent tumor growth and re‐challenge...
Although photothermal therapy (PTT) can noninvasively kill tumor cells and exert synergistic immunological effects, the immune responses are usually harmed due to the lack of cytotoxic T cells (CTLs) pre‐infiltration and co‐existing of intricate immunosuppressive tumor microenvironment (TME), including the programmed cell death ligand 1 (PD‐L1)/cluster of differentiation 47 (CD47)/regulatory T cells...
Developing various nanocomposite microwave absorbers is a crucial means to address the issue of electromagnetic pollution, but remains a challenge in satisfying broadband absorption at low thickness with dielectric loss materials. Herein, an ultra‐broadband microwave metamaterial absorber (MMA) based on hollow carbon/MXene/Mo2C (HCMM) is fabricated by a multi‐scale design strategy. The microscopic...
Natural bacteria are interesting subjects for cancer treatments owing to their unique autonomy‐driven and hypoxic target properties. Genetically modified bacteria (such as bacteria with msbB gene and aroA gene modifications) can effectively cross sophisticated physiological barriers and transport antitumor agents into deep tumor tissues, and they have good biosafety. Additionally, bacteria can secrete...
The ever‐growing portable electronics and electric vehicle draws the attention of scaling up of energy storage systems with high areal‐capacity. The concept of thick electrode designs has been used to improve the active mass loading toward achieving high overall energy density. However, the poor rate capabilities of electrode material owing to increasing electrode thickness significantly affect the...
Acute kidney injury (AKI) is frequently triggered by abundant reactive oxygen/nitrogen species (RONS) and leads to high morbidity and mortality in clinic. Unfortunately, the current clinical treatment options are only limited to supportive care, and hence, the development of nano‐antioxidants with high kidney enrichment is an attractive novel strategy for AKI management. Herein, self‐assembled ultrasmall...
In article number 2005113, Peng Huang and co‐workers develop biodegradable self‐assembled ultrasmall nanodots, which are composed of iron ion, gallic acid, and polyvinylpyrrolidone, as broad‐spectrum reactive oxygen/nitrogen species scavengers (RONS) with preferential kidney accumulation and rapid excretion to alleviate both glycerinum‐ and cis‐platinum‐induced acute kidney injury in mice.
Lead halide perovskite quantum dots (QDs) are promising materials for next‐generation photoelectric devices because of their low preparation costs and excellent optoelectronic properties. In this study, the blinking mechanisms and the intrinsic quantum‐confined Stark effect (IQCSE) in single organic–inorganic hybrid CH3NH3PbBr3 perovskite QDs using single‐dot photoluminescence (PL) spectroscopy is...
Chemical transformation in cellular environment is critical for regulating biological processes and metabolic pathways. Harnessing biocatalytic cascades to produce chemicals of interest has become a research focus to benefit industrial and pharmaceutic areas. Nanoreactors, which can act as artificial cell‐like devices to organize cascade reactions, have been recently proposed for potential therapeutic...
Chemodynamic therapy (CDT) has attracted considerable attention recently, but the poor reaction kinetics restrict its practical utility in clinic. Herein, glucose oxidase (GOx) functionalized ancient pigment nanosheets (SrCuSi4O10, SC) for programmable near‐infrared II (NIR‐II) photothermal‐enhanced starvation primed CDT is developed. The SC nanosheets (SC NSs) are readily exfoliated from SC bulk...
Tumor‐microenvironment‐responsive theranostics have great potential for precision diagnosis and effective treatment of cancer. Polyaniline (PANI) is the first reported pH‐responsive organic photothermal agent and is widely used as a theranostic agent. However, tumor pH‐responsive PANI‐based theranostic agents are not explored, mainly because the conversion from the emeraldine base (EB) to emeraldine...
The detection of Cu2+ in living plants and animals is of great importance for environment monitoring and disease diagnosis. Here, a near‐infrared (NIR) turn‐on photoacoustic (PA) probe (denoted as LET‐2) is developed for Cu2+ detection in living subjects, such as soybean sprouts and mice. The absorbance band of LET‐2 shifts from 625 to 715 nm after the interaction with Cu2+, thus producing strong...
Photoacoustic (PA) imaging (PAI) is a noninvasive and nonionizing biomedical imaging modality that combines the advantages of optical imaging and ultrasound imaging. Based on PAI, photoacoustic detection (PAD) is an emerging approach that is involved with the interaction between PA probes and analytes resulting in the changes of photoacoustic signals for molecular detection with rich contrast, high...
In article number 1602580, J. Lin, P. Huang, Y. Xu, Z. Li, and co‐workers present a light/pH dual‐stimuli responsive nanotheranostic for multimodal imaging such as two‐photon luminescence, fluorescence, photoacoustic, photothermal imaging, as well as trimodal synergistic therapy such as photothermal therapy, photodynamic therapy, and chemotherapy. The cover image depicts how this activatable theranostic...
Multimodal imaging guided synergistic therapy promises more accurate diagnosis than any single imaging modality, and higher therapeutic efficiency than any single one or their simple “mechanical” combination. Herein, we report a dual‐stimuli responsive nanotheranostic based on a hierarchical nanoplatform, composed of mesoporous silica‐coated gold nanorods (GNR@SiO2), Indocyanine Green (ICG), and 5‐fluorouracil...
A rapid, environment‐friendly, and cost‐effective finishing method has been developed for cotton textiles by using zwitterionic NCO‐sulfopropylbetaine as the antibacterial finishing agent through covalent bond. The sulfopropylbetaine‐finished cotton textile exhibits durable broad‐spectrum antibacterial and nonfouling activity, improved mechanical properties, and enhanced comfort.
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