Search results for: Majid Ghayour-Mobarhan

Items from 1 to 20 out of 198 results

article

Evaluating the Association of Anthropometric Indices With Total Cholesterol in a Large Population Using Data Mining Algorithms

Sahar Arab Yousefabadi, Somayeh Ghiasi Hafezi, Alireza Kooshki, Marzieh Hosseini, more

Journal of Clinical Laboratory Analysis > 38 > 17-18 > n/a - n/a

Background Unbalanced levels of serum total cholesterol (TC) and its subgroups are called dyslipidemia. Several anthropometric indices have been developed to provide a more accurate assessment of body shape and the health risks associated with obesity. In this study, we used the random forest model (RF), decision tree (DT), and logistic regression (LR) to predict total cholesterol based on new anthropometric...

article

Age‐specific reference intervals for liver function tests in healthy neonates, infants, and young children in Iran

Seyede Negin Badakhshan, Hamideh Ghazizadeh, Maryam Mohammadi‐Bajgiran, Habibollah Esmaily, more

Journal of Clinical Laboratory Analysis > 37 > 23-24 > n/a - n/a

Background The reference intervals (RIs) for liver function tests (LFTs) were determined in Iranian children for the first time. Methods A total of 344 healthy pediatrics aged 3 days to 30 months old were recruited. Serum levels of ALT, AST, ALP, direct bilirubin, and total bilirubin were measured. RIs were determined using CLSI Ep28‐A3 guidelines. Results All analytes demonstrated age‐specific...

article

Pediatric reference intervals for hematology parameters in healthy infants and young children in Iran

Maliheh Mohammadi, Hamideh Ghazizadeh, Maryam Mohammadi‐Bajgiran, Mary Kathryn Bohn, more

International Journal of Laboratory Hematology > 45 > 6 > 845 - 852

Introduction Defining accurate age‐ and sex‐specific reference intervals (RIs) for hematology parameters, especially for the pediatric population, is important for making an appropriate clinical diagnosis. To address gaps, we established age‐specific RIs for 11 hematologic parameters in Iranian children younger than 30 months for the first time. Methods Fresh whole blood samples collected from...

article

A large population‐based study on the prevalence of electrocardiographic abnormalities: A result of Mashhad stroke and heart atherosclerotic disorder cohort study

Sara Saffar Soflaei, Mahmoud Ebrahimi, Hamid Reza Rahimi, AmirAli Moodi Ghalibaf, more

Annals of Noninvasive Electrocardiology > 28 > 6 > n/a - n/a

Background Twelve‐lead electrocardiogram (ECG) is a common and inexpensive tool for the diagnostic workup of patients with suspected cardiovascular disease, both in clinical and epidemiological settings. The present study was designed to evaluate ECG abnormalities in Mashhad population. Methods ECGs were taken as part of MASHAD cohort study (phase1) and were coded according to the Minnesota coding...

article

Curcumin‐based nanoformulations alleviate wounds and related disorders: A comprehensive review

Legha Ansari, Habibeh Mashayekhi‐Sardoo, Vafa Baradaran Rahimi, Roghayeh Yahyazadeh, more

BioFactors > 49 > 4 > 736 - 781

Despite numerous advantages, curcumin's (CUR) low solubility and low bioavailability limit its employment as a free drug. CUR‐incorporated nanoformulation enhances the bioavailability and angiogenesis, collagen deposition, fibroblast proliferation, reepithelization, collagen synthesis, neovascularization, and granulation tissue formation in different wounds. Designing nanoformulations with controlled‐release...

article

Association of dietary and blood inflammatory indicators with depression, anxiety, and stress in adults with vitamin D deficiency

Payam Sharifan, Susan Darroudi, Mahdi Rafiee, Mansoureh Sadat Ekhteraei Toussi, more

International Journal of Geriatric Psychiatry > 38 > 8 > n/a - n/a

Background There is growing evidence that vitamin D may be related to mental health. The aim of the current study was to investigate the association of dietary and blood inflammatory factors with mental health disorders in subjects with vitamin D deficiency, shedding further light on the complex interplay of these conditions. Method In this cross‐sectional study, 306 subjects completed the validated...

article

Association between Inflammatory Factors, Vitamin D, Long Non‐Coding RNAs, MALAT1, and Adiponectin Antisense in Individuals with Metabolic Syndrome

Mohammad Rashidmayvan, Zahra Khorasanchi, Elyas Nattagh‐Eshtivani, Ali Jafarzadeh Esfehani, more

Molecular Nutrition & Food Research > 67 > 5 > n/a - n/a

Background Metabolic syndrome (MetS) is a common clustering of cardiovascular risk factors associated with increased inflammation. Long non‐coding RNA (LncRNA) are involved in many of the body's metabolic activities, including inflammation. Vitamin D may play a vital role in preventing metabolic syndrome risk factors. This study aimed to evaluate the status of inflammation and expression of LncRNA...

article

Data mining approaches for type 2 diabetes mellitus prediction using anthropometric measurements

Maryam Saberi‐Karimian, Amin Mansoori, Maryam Mohammadi Bajgiran, Zeinab Sadat Hosseini, more

Journal of Clinical Laboratory Analysis > 37 > 1 > n/a - n/a

Background The aim of this study was to evaluate the anthropometric measurements most associated with type 2 diabetes mellitus (T2DM) using machine learning approaches. Methods A prospective study was designed for a total population of 9354 (43% men and 57% women) aged 35–65. Anthropometric measurements include weight, height, demispan, Hip Circumference (HC), Mid‐arm Circumference (MAC), Waist...

article

Age and sex‐specific reference intervals for prooxidant‐antioxidant balance, anti‐heat‐shock protein 27 (anti‐hsp27), and routine laboratory tests in the middle‐aged adult population

Hamideh Ghazizadeh, Mary Kathryn Bohn, Mahdiyeh Yaghooti‐Khorasani, Roshanak Ghaffarian‐Zirak, more

Biotechnology and Applied Biochemistry > 69 > 3 > 1300 - 1310

Introduction We aimed to define specific reference intervals (RIs) for 11 biomarkers including inflammatory and oxidative stress biomarkers, liver, and renal function tests in a healthy Iranian adult population for the first time. Methods CLSI Ep28‐A3 guidelines were then used to calculate accurate age‐ and sex‐ as well as body mass index (BMI)‐specific RIs. Results RIs for studied biomarkers...

article

High‐density lipoprotein lipid peroxidation as a diagnostics biomarker in coronary artery disease

Shima Yazdandoust, Seyyed Mohammad Reza Parizadeh, Majid Ghayour‐Mobarhan, Parichehreh Yaghmaei, more

BioFactors > 48 > 3 > 634 - 642

This study aimed at evaluating the serum High‐density lipoprotein lipid peroxidation (HDLox) levels and their association with coronary artery disease (CAD). This case–control study comprised 572 patients with stable CAD and 281 healthy subjects with no history of cardiovascular disease (control group). Based on the results of coronary angiography, the patient group was divided into two groups: CAD−...

article

Altered triglyceride glucose index and fasted serum triglyceride high‐density lipoprotein cholesterol ratio predict incidence of cardiovascular disease in the Mashhad cohort study

Hassan Mirshafiei, Susan Darroudi, Majid Ghayour‐Mobarhan, Habibollah Esmaeili, more

BioFactors > 48 > 3 > 643 - 650

The triglyceride glucose (TyG) index and triglyceride/high lipoprotein density cholesterol (TG/HDL‐C) are two important risk markers to evaluate the insulin resistance and cardiovascular diseases (CVDs). To assess the association between TG/HDL‐C and TyG index and CVDs. The Mashhad stroke and heart association disorder cohort study started in 2010 and has been continued until 2020. During 6‐year follow‐up...

article

Interaction between the genetic variant of rs696217‐ghrelin and food intake and obesity and dyslipidemia

Mehran Yadegari, Reza Zare‐Feyzabadi, Mohanna Zakariaeiseraji, Reza Sahebi, more

Annals of Human Genetics > 86 > 1 > 14 - 23

In this study, we aimed to investigate the relationship between the genetic variant of rs696217‐ghrelin and fasted lipid profile, indices of obesity, and environmental parameters. Amplification refractory mutation system‐polymerase chain reaction (ARMs‐PCR) was used for genotyping 1118 individuals recruited as part of the Mashhad Stroke and Heart Atherosclerotic Disorder (MASHAD) cohort study. The...

article

A pilot study of the effects of crocin on high‐density lipoprotein cholesterol uptake capacity in patients with metabolic syndrome: A randomized clinical trial

Maryam Saberi‐Karimian, Hamideh Safarian‐Bana, Elham Mohammadzadeh, Tooba Kazemi, more

BioFactors > 47 > 6 > 1032 - 1041

A randomized clinical trial high‐density lipoprotein (HDL) cholesterol uptake capacity (CUC) is reduced in patients with metabolic syndrome (MetS). We have assessed the effect of crocin supplementation on HDL CUC in patients with MetS. Forty‐four subjects with MetS were randomly allocated to one of two groups: one group received placebo and the other group received crocin at a dose of 30 mg (two...

article

Association of ANGPTL3 polymorphisms with high‐density lipoprotein cholesterol uptake capacity in patients with cardiovascular disease

Malihe Aghasizadeh, Mina Nosrati, Maryam Saberi‐Karimian, Hamideh Safarian, more

Journal of Clinical Laboratory Analysis > 35 > 12 > n/a - n/a

Introduction Previous studies have shown the importance of angiopoietin‐like 3 (ANGPTL3) as a modulator of lipid profiles. Cholesterol uptake capacity (CUC) is one means for assessing high‐density lipoprotein (HDL) functionality. This study for the first time has investigated the relationship between genetic ANGPTL3 polymorphism and CUC in patients with cardiovascular disease. Methods Five hundred...

article

Comparative effects of on‐pump versus off‐pump coronary artery bypass grafting surgery on serum cytokine and chemokine levels

Seyed Reza Mirhafez, Seyedeh Hamideh Khadem, Amirhossein Sahebkar, Ali Movahedi, more

IUBMB Life > 73 > 12 > 1423 - 1431

Coronary artery bypass grafting (CABG) surgery with two methods (on‐pump or off‐pump) can be used to rescue individuals with severe coronary artery disease (CAD). Each method might cause an inflammatory response, which can lead to some complications. The aim of this study was to compare the changes in serum concentrations of IFN‐γ, tumor necrosis factor (TNF)‐α, interleukin (IL)‐1α, IL‐1β, IL‐2, IL‐4,...

article

Factors determining the serum 25‐hydroxyvitamin D response to vitamin D supplementation: Data mining approach

Zahra Amiri, Mina Nosrati, Payam Sharifan, Sara Saffar Soflaei, more

BioFactors > 47 > 5 > 828 - 836

Vitamin D supplementation has been shown to prevent vitamin D deficiency, but various factors can affect the response to supplementation. Data mining is a statistical method for pulling out information from large databases. We aimed to evaluate the factors influencing serum 25‐hydroxyvitamin D levels in response to supplementation of vitamin D using a random forest (RF) model. Data were extracted...

article

Age‐ and sex‐specific reference intervals for superoxide dismutase enzyme and several minerals in a healthy adult cohort

Hamideh Ghazizadeh, Mary Kathryn Bohn, Mahdiyeh Yaghooti‐Khorasani, Atieh Kamel Khodabandeh, more

Journal of Clinical Laboratory Analysis > 35 > 9 > n/a - n/a

Introduction The aim of this study was to establish RIs for clinically important markers including superoxide dismutase (SOD), serum copper, zinc, calcium, magnesium, and phosphate in a cohort of healthy Iranian adults. Materials A subsample from MASHAD cohort study was used to assess serum SOD, copper, zinc, calcium, magnesium and phosphate. Serum SOD was measured according to its inhibitory potential...

article

The effects of honey on pro‐ and anti‐inflammatory cytokines: A narrative review

Narges Navaei‐Alipour, Mohadeseh Mastali, Gordon A. Ferns, Maryam Saberi‐Karimian, more

Phytotherapy Research > 35 > 7 > 3690 - 3701

Honey contains flavonoids and phenolic acids, and because of their antioxidant and anti‐inflammatory properties, they may play an important role in human health. The purpose of this review was to synthesize the effects of natural honey on pro‐ and anti‐inflammatory cytokines. The effects of honey on wound healing and immunity appear to be inconsistent. The available databases )PubMed and Scopus) were...

article

Serum HDL cholesterol uptake capacity in subjects from the MASHAD cohort study: Its value in determining the risk of cardiovascular endpoints

Malihe Aghasizadeh, Sara Samadi, Amirhossein Sahebkar, Ebrahim Miri‐Moghaddam, more

Journal of Clinical Laboratory Analysis > 35 > 6 > n/a - n/a

Background The efficiency of high‐density lipoprotein (HDL) to efflux cholesterol contributes to the reverse cholesterol transport (RCT) pathway as one of HDL’s proposed functions and depends on the ability of HDL to uptake cholesterol. We aimed to investigate cholesterol uptake capacity (CUC) by a newly developed assay in samples from the MASHAD (Mashhad Stroke and Heart Atherosclerotic Disorders)...

article

A systematic review of preclinical studies on the efficacy of propolis for the treatment of inflammatory bowel disease

Davood Soleimani, Mahsa Miryan, Helda Tutunchi, Jamshid G. Navashenaq, more

Phytotherapy Research > 35 > 2 > 701 - 710

Propolis is a resinous substance produced by bees from plants. There has been some evidence indicating that propolis may be a candidate for the treatment of inflammatory bowel disease (IBD) because of its potent antioxidant properties and ability to modulate immune response and gut microbiome. The objective of this systematic review was to investigate the role of propolis in the treatment of IBD,...

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Search results for: Majid Ghayour-Mobarhan

Evaluating the Association of Anthropometric Indices With Total Cholesterol in a Large Population Using Data Mining Algorithms

Age‐specific reference intervals for liver function tests in healthy neonates, infants, and young children in Iran

Pediatric reference intervals for hematology parameters in healthy infants and young children in Iran

A large population‐based study on the prevalence of electrocardiographic abnormalities: A result of Mashhad stroke and heart atherosclerotic disorder cohort study

Curcumin‐based nanoformulations alleviate wounds and related disorders: A comprehensive review

Association of dietary and blood inflammatory indicators with depression, anxiety, and stress in adults with vitamin D deficiency

Association between Inflammatory Factors, Vitamin D, Long Non‐Coding RNAs, MALAT1, and Adiponectin Antisense in Individuals with Metabolic Syndrome

Data mining approaches for type 2 diabetes mellitus prediction using anthropometric measurements

Age and sex‐specific reference intervals for prooxidant‐antioxidant balance, anti‐heat‐shock protein 27 (anti‐hsp27), and routine laboratory tests in the middle‐aged adult population

High‐density lipoprotein lipid peroxidation as a diagnostics biomarker in coronary artery disease

Altered triglyceride glucose index and fasted serum triglyceride high‐density lipoprotein cholesterol ratio predict incidence of cardiovascular disease in the Mashhad cohort study

Interaction between the genetic variant of rs696217‐ghrelin and food intake and obesity and dyslipidemia

A pilot study of the effects of crocin on high‐density lipoprotein cholesterol uptake capacity in patients with metabolic syndrome: A randomized clinical trial

Association of ANGPTL3 polymorphisms with high‐density lipoprotein cholesterol uptake capacity in patients with cardiovascular disease

Comparative effects of on‐pump versus off‐pump coronary artery bypass grafting surgery on serum cytokine and chemokine levels

Factors determining the serum 25‐hydroxyvitamin D response to vitamin D supplementation: Data mining approach

Age‐ and sex‐specific reference intervals for superoxide dismutase enzyme and several minerals in a healthy adult cohort

The effects of honey on pro‐ and anti‐inflammatory cytokines: A narrative review

Serum HDL cholesterol uptake capacity in subjects from the MASHAD cohort study: Its value in determining the risk of cardiovascular endpoints

A systematic review of preclinical studies on the efficacy of propolis for the treatment of inflammatory bowel disease

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