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BACKGROUND:The sensitivity of urinary cytology for the diagnosis of urothelial carcinomas is low, particularly in low‐grade carcinomas. The UroVysion test is a fluorescent in situ hybridization multiprobe assay that increases the sensitivity of urinary cytology. However, this test is not widely available. P16INK4a, a protein involved in cell cycle progression, is overexpressed in urothelial carcinoma...
BACKGROUND:Non–muscle‐invasive urothelial cell carcinoma (NMIUCC) has a high tendency to recur and affected patients must be monitored regularly using invasive cystoscopies. The aim of the current study was to compare a multicolor fluorescence in situ hybridization (FISH) assay (UroVysion) with routine follow‐up (cystoscopy and cytology) in the monitoring of patients with a previous history of NMIUCC...
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