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Homomeric complexes of 5-HT3A receptor subunits form a ligand-gated ion channel. This assembly does not fully reproduce the biophysical and pharmacological properties of native 5-HT3 receptors which might contain the recently cloned 5-HT3B receptor subunit. In the present study, heteromeric assemblies containing human 5-HT3A and 5-HT3B subunits were expressed in HEK 293 cells to detail the functional...
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