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Positron emission tomography (PET) using F-18 sodium fluoride (NaF) has been investigated as an imaging biomarker for coronary vulnerable plaque. The goal of this work is to study the effects of activity uptake of the plaque, image noise, respiratory and cardiac motion, and respiratory and cardiac gating techniques on the detectability of coronary artery plaques through a realistic simulation study...
We investigated the performance of a post reconstruction dual respiratory and cardiac (R&C) motion compensation method for improved image quality of 4D cardiac gated small animal myocardial perfusion (MP) SPECT images. A normal mouse was injected with ∼8 mCi of Tc-99m sestamibi, anesthetized, fitted with ECG leads for cardiac gating signal acquisition, and placed on top of a pressure gauge bellow...
The current work was based on a previously developed 4D image reconstruction method for myocardial perfusion (MP) PET where dual respiratory motion (RM) and cardiac motion (CM) compensation were performed post reconstruction. We implemented and extended the work on patient data from a commercial PET system and demonstrated further image quality improvement. We divided the PET events into 6 equal-count...
The goal of this study is to develop and evaluate two 4D statistical iterative image reconstruction (SIIR) methods with respiratory motion (RM) and cardiac motion (CM) compensation for improving the detection of motion defects in 4D gated cardiac PET. The first 4D SIIR method, motion correction after reconstruction (MCAR) was developed previously, where the dual RM&CM compensation was achieved...
<?Pub Dtl?>This paper presents a novel CMOS hybrid rectifier that can simultaneously and efficiently scavenge energy from a low-amplitude radio-frequency (RF) signal and a low-frequency, low-energy signal from a piezoelectric (PZT) transducer. The piezoelectric signal is used for biasing a complimentary, cross-coupled rectifier (CCCR) chain to an operating point such that the RF signal energy...
Respiratory motion is one image degradation factor that affects the resolution and may cause artifacts in PET imaging. Respiratory gating technique is able to reduce the blurring effects but results in higher noise level. Conventional motion correction methods that model motion effects during or after image reconstruction not only increases reconstruction time, but also requires a gated or blurred...
We developed a 4D SPECT image reconstruction method with respiratory motion (RM) and cardiac motion (CM) compensation, and evaluated its performance using a previously developed 4D channelized Hotelling observer (CHO) model for the task based evaluation of 4D medical images. A series of 4D XCAT (eXtended CArdiac Torso) phantoms with and without a regional CM abnormality was generated that divided...
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