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Insertion behaviour of microneedle (MN) arrays depends upon the mechanical properties of the skin and, MN geometry and distribution in an array. In addressing this issue, this paper studies MN array insertion mechanism into skin and provides a simple quantitative basis to relate the insertion force with distance between two MNs. The presented framework is based on drawing an analogy between a beam...
Transdermal drug delivery is a promising approach that allows controlled release of drug over time while avoiding possible degradation due to the gastrointestinal tract or first-pass liver effect. Of many different methods have been employed in transdermal drug delivery, microneedle is a widely explored MEMS-based device that can conveniently penetrate the skin and thus create micrometer-scale openings...
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