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Breast cancer is one of the most common malignancies of women. Assessing the biological parameters of malignant tumors may facilitate predictions of clinical outcome. The expression of the three catalytic subunits of protein phosphatase (PP) type 1, PP1α, PP1γ1 and PP1δ, as well as the one catalytic subunit of PP type 2, PP2AC, were examined in ten cases of mammary dysplasia, ten cases of fibroadenoma...
A mutant strain (LEC) of rats was found to possess the feature of low degree of the zinc-induced hepatic metallothionein (MT) gene expression due to an alteration of the transcription factor concerned in the gene expression. Northern blot analyses showed that the amount of MT-I mRNA induced by intraperitoneal zinc injection is smaller in LEC mutant rat liver than in normal rat liver, while the amount...
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