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α-Melanocyte stimulating hormone (α-MSH) has been shown to inhibit the production and the effects of pro-inflammatory cytokine by inflammatory cells in innate immunity. We have determined whether α-MSH inhibits anti-CD3/CD28-mediated spleen cells and CD4 + CD25 − T cells proliferation and its mechanism of action. The proliferation of anti-CD3/CD28-mediated spleen cells and CD4 ...
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