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In the present study, chemometric analysis of UV spectral data of cyclodextrin guest–host complexes was used to develop multivariate regression models that were subsequently used to determine the enantiomeric composition of samples of ibuprofen and norephedrine. Partial-least-squares regression models (PLS-1) were made for both compounds with α-, β-, γ-cyclodextrins (CDs). Using a regression model...
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