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Caspase-3 plays a vital role in intrinsic and extrinsic pathways of programed cell death and in cell proliferation. Its detection is an important tool for early detection of some cancers and apoptosis-related diseases, and for monitoring the efficacy of pharmaceuticals and of chemo- and radiotherapy of cancers. This review (with 72 references) summarizes nanomaterial based methods for signal amplification...
Caspases, especially caspase-3, play a critical role in the intrinsic and extrinsic pathways of apoptosis. In addition, caspase-3 is involved in mental disorders like Alzheimer disease. Any up and down regulation of caspase-3 activity may cause cancer. This review (with 58 references) summarizes recent advances in electrochemical and electrochemiluminescent quantitation of the activity of caspase-3...
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