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Multiple binding sites participate in the interaction between the nicotinic acetylcholine receptor (nAChR) and α-bungarotoxin (α-BgTx).We have previously reported the involvement of two histidine residues in such interaction and that His 134, which belongs to the cysteinyl loop α124-127, being one of them.In this work we study the possible role of His 186, included in the α185-200 toxin binding determinant...
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