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Antisense RNA expression was used to assess the role of the interleukin 2 receptor (IL2R) α-chain in proliferation of T cells transformed by infection with the intracellular parasite Theileria parva. Two vectors were constructed, in which part of the bovine IL2R α-chain cDNA was inserted in either a sense or antisense orientation in the plasmid pHS1-CAT, which is expressed by induction of the human...
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