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Osteoarthritis (OA) is the most common musculoskeletal disease, affecting millions of individuals worldwide. New treatment approaches require an understanding of the pathophysiology of OA and its biomechanical, inflammatory, genetic, and environmental risk factors. The purpose of animal models of OA is to reproduce the pattern and progression of degenerative damage in a controlled fashion, so that...
The compressive loads produced in the medial compartment of a rabbit knee during hopping are unknown, and necessary for the development of an animal model to study unicompartmental osteoarthritis.In an effort to obtain such data, a surgical procedure was developed to insert a pressure sensor into the medial tibial compartment of a New Zealand white rabbit knee joint, and an inactive sensor of the...
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