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PurposeSecreted protein acidic and rich in cysteine (SPARC) is one of the first known matricellular proteins that modulates interactions between cells and extracellular matrix. Recent studies investigated the clinical significance of SPARC gene expression in the development, progression, and metastasis of cancer. The present study examined the relations of the relative expression of the SPARC gene...
BackgroundMatrix metalloproteinases are members of a large family of endopeptidases that participate in the extracellular‐matrix degradation that accompanies cancer cell invasion, metastasis and angiogenesis. The membrane‐type 1 matrix metalloproteinase (MT1‐MMP) gene has been reported in various cancers and is associated with tumor invasion and metastasis. This study examined the relation of the...
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