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Brain neurosteroids modulate gamma-aminobutyric acid type A (GABA A ) receptor activity, thereby playing a role in mood disorders. Alterations in 17β-estradiol (E 2 ) and progesterone (P) are also known to play a significant role in psychopathology in women. The aim of the present study was to evaluate the synthesis of dihydroprogesterone (DHP), tetrahydroprogesterone (THP), and the...
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