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Background
Allogeneic hematopoietic stem cell transplantation (HCT) performed in children from human leukocyte antigen (HLA)‐identical related donors is associated with very high survival rates and disease‐free survival. Patients are exposed to gonadotoxic alkylating agents or irradiation in the HCT conditioning regimen. Consequently, infertility is a major long‐term complication of HCT for sickle...
Background
Improved outcomes and the availability of clinical trials of hematopoietic cell transplantation (HCT) from alternate donors and genetically modified autologous hematopoietic progenitor cells have expanded the applicability of HCT for sickle cell disease (SCD). To understand the perspective of primary caregivers exploring HCT in the current milieu, we asked the research question “What motivates...
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