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Activated B cells are selected for in germinal centers by regulation of their apoptosis. The Ca2+‐binding cytoskeletal adaptor protein Swiprosin‐1/EFhd2 (EFhd2) can promote apoptosis in activated B cells. We therefore hypothesized that EFhd2 might limit humoral immunity by repressing both the germinal center reaction and the expected enhancement of immune responses in the absence of EFhd2. Here, we...
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