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Serotonin transporters (SERTs) have been implicated in various neuropsychiatric disorders. We aim to validate 4-[ 18 F]-ADAM (N,N-dimethyl-2-(2-amino-4-[ 18 F]fluorophenylthio)benzylamine) as a SERT imaging agent in rats using micro-positron emission tomography (micro-PET) and autoradiography. Sixty to ninety min after injecting 4-[ 18 F]-ADAM, specific uptake ratios (SURs)...
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