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Festuca pratensis (meadow fescue) infected with the endophyte Acremonium uncinatum produces loline alkaloids (1-aminopyrrolizidines) that are not found in the uninfected grass or the fungus alone. Five alkaloids were identified by capillary GC and GC-MS: N-formylloline as the major compound, followed byN -acetylloline, N-acetylnorloline and trace amounts of loline and N-methylloline. A routine procedure...
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