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We evaluated the cerebral metabolic rate of glucose (CMRGlu) and cerebral blood flow (CBF) after unilateral lesioning of the rat basal forebrain cholinergic projection system using ibotenic acid. Using positron emission tomography, we measured CMRGlu and CBF with [ 18 F]-2-fluoro-2-deoxy-d-glucose (FDG) and with H 215 O, respectively. Three days after surgery, CMRGlu...
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