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The mouse Snurf/Snrpn gene has two differentially methylated regions (DMRs), the maternally methylated region at the 5′ end (DMR1) and the paternally methylated region at the 3′ end (DMR2). DMR1, a region that includes the Snrpn promoter and the entire intron 1, has been thought to be a germline DMR, which inherits the parental-specific methylation profile from the gametes. DMR1 is not only associated...
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