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Representation and evaluation methods for statistically predicting organ shapes from neighboring organ shapes are described. In order to fully utilize the constraints on interrelations of multiple organ shapes, various extents of sub-shapes of organs are considered based on their proximity instead of just using the whole organ shapes. The prediction power are evaluated for various extents of sub-shapes...
In this paper, we report our current progress results on computer assisted diagnostic (CAD) system, which consists of three units: database unit (statistical atlas of human anatomy), image processing unit (image enhancement, image segmentation, image registration), and visualization unit (volume rendering). In the database unit, we proposed a new method called generalized N-dimensional principal component...
In computational anatomy, statistical shape model is used for quantitative evaluation of the variations of an organ shape. This paper is focused on construction of Statistical Shape Model of the liver and its application to computer assisted diagnosis. We prove the potential application of statistical shape models in classification of normal and cirrhosis livers. First, statistical shape model of...
In this paper, we propose a new method to detect liver tumors in CT images automatically. The proposed method is composed of two steps. In the first step, tumor candidates are extracted by EM/MPM algorithm; which is used to cluster liver tissue. To cluster a dataset, EM/MPM algorithm exploits both intensity of voxels and labels of the neighboring voxels. It increases the accuracy of detection, with...
Segmentation of liver in CT images is regarded as a challenge in image processing due to low-contrast of datasets, variety of liver shape, and its non-uniform texture; especially for abnormal cases. In this paper, we deal with normal and abnormal datasets as images containing two or more Gaussian components. We threshold a slice in a narrow band of each mode, find liver pixels based on a priori knowledge,...
A computational framework is presented for 3-D liver shape approximation and characterization in order to determine the accuracy of shape reconstruction via Spherical Harmonics expansion. Spherical Harmonics is a powerful mathematical tool for expanding the shape. But in medical domain, livers have very variation geometry, in shape, size, and volume. In this regards, we evaluated and optimized the...
In image guided surgery, the registration of pre- and intra-operative image data is an important issue. In registrations, we seek an estimate of the transformation that registers the reference image and test image by optimizing their metric function (similarity measure). To date, local optimization techniques, such as the gradient decent method, are frequently used for medical image registrations...
Recently a growing interest has been seen in minimally invasive treatments with open configuration magnetic resonance (Open-MR) scanners. In this paper, we proposed a semi-automatic non-rigid 3D MR-CT image registration technique for MR-Guided Liver Cancer Surgery in which cancer tissues are coagulated by microwave ablation. Because of the lower magnetic field (0.5 T) and various different surgical...
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