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Objectives
The role of celecoxib in preventing and treating tumors has attracted broad attention in recent years because of its selective and specific inhibition of COX‐2 activity. We investigated the inhibitory effects and mechanisms of celecoxib combined with 5‐fluorouracil (5‐FU) on proliferation of squamous cell carcinoma cells in vivo and in vitro.
Study Design
Animal study and basic research...
Objectives/HypothesisValidating an antiadhesive strategy to prevent anterior glottic web (AGW) development.
Study DesignProspective animal study in rabbits.
MethodsFifteen New Zealand white rabbits were randomly divided into three equal groups (five rabbits each), applying either HyFence (HF: 0.1 g/vocal fold), an antiadhesive test agent; mitomycin‐C (MMC: 1 mg/ml, 4 min) as reference therapy; or...
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