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Fourteen judiciously selected reversed phase columns were tested with 18 cationic drug solutes under the isocratic elution conditions advised in the Snyder–Dolan (S–D) hydrophobic subtraction method of column classification. The standard errors (S.E.) of the least squares regressions of logk′ vs. logk′ REF were obtained for a given column against a reference column and used to compare and...
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