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As a steady stream of electronic devices being discarded, a vast amount of electronic substrate waste of petroleum‐based nondegradable polymers is generated, raising endless concerns about resource depletion and environmental pollution. With coupled reagent (CR)‐grafted artificial marble waste (AMW@CR) as functional fillers, polylactic acid (PLA)‐based highly stretchable biodegradable green composite...
Oral antioxidant nanozymes bring great promise for inflammatory bowel disease (IBD) treatment. To efficiently eliminate reactive oxygen species (ROS), various metal‐based nanozymes have been developed for the treatment of IBD but their practical applications are seriously impaired by unstable ROS‐eliminating properties and potential metal ion leakage in the digestive tract. Here, the authors for the...
Autophagy
To overcome the autophagy compromised mechanism of protective cellular processes by “eating” damaged organelles or potentially toxic materials in tumor cells, Nan Li and co‐workers show how tellurium double‐headed nanobullets (TeDNBs)‐HO is utilized to induce autophagy dysfunction. On the one hand, TeDNBs‐mediated endoplasmic reticulum stress could excessively induce autophagy; thus, resulting...
To overcome the autophagy compromised mechanism of protective cellular processes by “eating”/“digesting” damaged organelles or potentially toxic materials with autolysosomes in tumor cells, lysosomal impairment can be utilized as a traditional autophagy dysfunction route for tumor therapy; however, this conventional one‐way autophagy dysfunction approach is always limited by the therapeutic efficacy...
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