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Snake venom group IA secretory phospholipase A 2 (sPLA 2 -IA) is known as a neurotoxin. Snake venom sPLA 2 s are neurotoxic in vivo and in vitro, causing synergistic neurotoxicity to cortical cultures when applied with toxic concentrations of glutamate. However, it has not yet been cleared sufficiently how sPLA 2 -IA exerts neurotoxicity. Here, we found sPLA 2 ...
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