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Transient receptor transient receptor potential vanilloid 1 (TRPV1) is a Ca2+-permeable channel gated by oxidative stress and capsaicin (CAP) and modulated by melatonin (MEL) and capsazepine (CPZ). A combination of doxorubicin (DOX) and MEL may offer a potential therapy for breast cancer by exerting antitumor and anti-apoptotic effects and modulating Ca2+ influx and TRPV1 activity. We aimed to investigate...
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