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Background and AimThe aim of this study is to evaluate the effect of metformin on intestinal inflammation.
MethodsCOLO205 cells were pretreated with metformin and stimulated with tumor necrosis factor (TNF)‐α. Expression of interleukin (IL)‐8 was determined by luciferase assay and real‐time PCR. Inhibitor of kappaB (IκB) phosphorylation/degradation and adenosine monohosphate‐activated protein kinase...
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