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Haemophilus parasuis causes serious economic losses in pigs, which is the etiology of Glässer's disease. In this study we studied the immunogenicity of proteins encoded by the hxuCBA gene cluster in H. parasuis. Through bioinformatics analysis, HxuC, HxuB, and HxuA proteins were found that they might have strong antigenicity, with 31 putative cytotoxic T-lymphocyte (CTL) epitopes and multiple B-cell...
A complete open reading frame of htrA gene and its encoding protein of Haemophilus parasuis were analyzed by multiple bioinformatics software. The htrA gene was composed of 1380 bp nucleotides encoding HtrA protein of 459 amino acids. The molecular weight of the protein was 48494.4 Da with the formula C2140H3505N597O665S8. The HtrA protein had the following characteristics: one signal peptide cleavage...
This study used a comparative proteomics approach to distinguish between the two-dimensional electrophoresis profiles of extracellular proteins in Nagasaki and SW114. Protein spots were identified using matrix-assisted laser desorption/ionization tandem time-of-flight mass spectrometry. The ten proteins unique to Nagasaki were putative adhesin AidA protein, putative extracellular serine protease (autotransporter)...
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