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The analgesic and antihyperalgesic effects of dipyrone, meloxicam or a dipyrone–meloxicam combination were compared in dogs undergoing elective ovariohysterectomy. In a double-blinded, prospective, randomised design, 40 bitches premedicated with intramuscular pethidine (4 mg/kg) and anaesthetised with isoflurane received one of four intravenous treatments (n = 10 per group) before ovariohysterectomy:...
The effects of epidural and intravenous (IV) methadone (0.5mg/kg) on the minimum alveolar concentration of isoflurane (ISO MAC ) were compared in dogs. Six dogs (16.5±2.5kg bodyweight) received three treatments in random order during isoflurane anaesthesia, with a 7day washout interval between each study. Methadone was injected via a lumbosacral epidural catheter introduced 10cm cranially...
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