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Liver X receptors (LXRs)-mediated signals in acanthoic acid (AA) ameliorating liver fibrosis were examined in carbon tetrachloride (CCl 4 )-induced mice and TGF-β stimulated hepatic stellate cells (HSCs). AA was isolated from the root of Acanthopanax koreanum Nakai (Araliaceae). CCl 4 -treated mice were intraperitoneally injected with 10% CCl 4 in olive oil (2mL/kg for 8weeks)...
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