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Dynamic-contrast enhanced magnetic resonance imaging (DCE–MRI) is used for detailed characterization of pathology of lesions sites, such as brain tumors, by quantitative analysis of tracer’s data through the use of pharmacokinetic (PK) models. A key component for PK models in DCE–MRI is the estimation of the concentration–time profile of the tracer in a nearby vessel, referred as Arterial Input Function...
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