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Observational studies showed that obesity is a major risk factor for peripheral arterial disease (PAD). However, conventional epidemiology studies are vulnerable to residual bias from confounding factors. We aimed to explore the causality of obesity in development of PAD using Mendelian Randomization (MR) approach.A MR analysis was performed in 11,477 community-dwelling adults aged 40 years and above...
Adipocyte and epidermal fatty acid-binding protein (A-FABP, E-FABP) are cytoplasmic proteins which may play an important role in metabolic diseases. In the present study, we investigated the different association of A-FABP and E-FABP with metabolic syndrome (MetS) and coronary artery disease (CAD) in Chinese adults.A total of 459 subjects (233 MetS and 226 non-MetS) who had undergone coronary angiography...
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