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IL-13 receptor α2 (IL-13Rα2) binds IL-13 with high affinity and modulates IL-13 responses. There are soluble and membrane forms of IL-13Rα2 generated by alternative splicing in mice, but human subjects express only the membrane form of IL-13Rα2 (memIL-13Rα2).We determined the role of memIL-13Rα2 in the development of allergic inflammation in mouse models of asthma.IL-13Rα2–deficient and memIL-13Rα2...
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