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Objective To evaluate the efficacy of enalapril treatment on decline in glomerular filtration rate and reduction in proteinuria in children with chronic kidney disease (CKD). Design Open-label, randomized controlled trial. Setting Pediatric nephrology clinic at a tertiary-care referral hospital. Intervention Children with GFR between 15–60 mL/min/1.73 m2 were randomized to receive either enalapril...
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