Search results for: Seppo Salminen

Items from 1 to 20 out of 92 results

article

The ability of human intestinal anaerobes to metabolize different oligosaccharides: Novel means for microbiota modulation?

Riichi Ose, Katsuaki Hirano, Shintaro Maeno, Junichi Nakagawa, more

Anaerobe > 2018 > 51 > C > 110-119

Prebiotic oligosaccharides are known to have significant impacts on gut microbiota and are thus widely used to program healthy microbiota composition and activity from infants to the elderly. Bifidobacteria and lactobacilli are among the major target microorganisms of oligosaccharides, but the metabolic properties of oligosaccharides in other predominant gut microbes have not been well characterized...

article

The impact of probiotic supplementation during pregnancy on DNA methylation of obesity-related genes in mothers and their children

Sanna Vähämiko, Asta Laiho, Riikka Lund, Erika Isolauri, more

European Journal of Nutrition > 2019 > 58 > 1 > 367-377

Purpose Dietary supplementation with probiotics during pregnancy has been suggested to decrease the risk for obesity in women after delivery and to minimize excessive weight gain in their children. Epigenetic DNA methylation has been proposed to impact on gene activity, thereby providing a plausible molecular mechanism for a broad range of biological processes and diseases. This pilot study aimed...

article

Proceedings of the 2017 WAO Symposium on Hot Topics in Allergy: Pediatric & Regulatory Aspects

Giovanni Traina, Rocco Luigi Valluzzi, Vincenzo Fierro, Carla Riccardi, more

World Allergy Organization Journal > 2017 > 10 > 2 > 1-16

article

Correlation between in vitro and in vivo assays in selection of probiotics from traditional species of bacteria

Gabriel Vinderola, Miguel Gueimonde, Carlos Gomez-Gallego, Lucrecia Delfederico, more

Trends in Food Science & Technology > 2017 > 68 > C > 83-90

In vitro selection tests such as exposure to low pH and bile salts, competitive exclusion of pathogens, adherence to cell lines and prokaryotic-eukaryotic co-cultures have been commonly used to predict the functional properties of lactobacilli and bifidobacteria for their use as probiotics. However, the correlation of in vitro results with in vivo performance remains obscure.To review the current...

article

Long‐term safety and efficacy of perinatal probiotic intervention: Evidence from a follow‐up study of four randomized, double‐blind, placebo‐controlled trials

Krista Lundelin, Tuija Poussa, Seppo Salminen, Erika Isolauri

Pediatric Allergy and Immunology > 28 > 2 > 170 - 175

Background Societies worldwide are faced with a progressive increase in immune‐mediated health problems such as allergic, autoimmune, and inflammatory diseases, as well as obesity. Perinatal administration of specific probiotic bacteria is an attractive approach in reducing the risk of these conditions, but long‐term efficacy and safety data are lacking. The aim here was to evaluate the clinical...

article

A canine-specific probiotic product in treating acute or intermittent diarrhea in dogs: A double-blind placebo-controlled efficacy study

Carlos Gómez-Gallego, Jouni Junnila, Sofia Männikkö, Pirkko Hämeenoja, more

Veterinary Microbiology > 2016 > 197 > C > 122-128

A double-blind placebo-controlled intervention study on 60 dogs recruited from a pool of canine patients visiting a veterinary practice and diagnosed with acute diarrhea was conducted. The dogs received in randomized manner either a sour-milk product containing three canine-derived Lactobacillus sp. probiotics in combination of Lactobacillus fermentum VET 9A, L. rhamnosus VET 16A, and L. plantarum...

article

The human milk microbiome and factors influencing its composition and activity

Carlos Gomez-Gallego, Izaskun Garcia-Mantrana, Seppo Salminen, María Carmen Collado

Seminars in Fetal and Neonatal Medicine > 2016 > 21 > 6 > 400-405

Beyond its nutritional aspects, human milk contains several bioactive compounds, such as microbes, oligosaccharides, and other substances, which are involved in host–microbe interactions and have a key role in infant health. New techniques have increased our understanding of milk microbiota composition, but few data on the activity of bioactive compounds and their biological role in infants are available...

article

Genomic characterization of a fructophilic bee symbiont Lactobacillus kunkeei reveals its niche-specific adaptation

Shintaro Maeno, Yasuhiro Tanizawa, Yu Kanesaki, Eri Kubota, more

Systematic and Applied Microbiology > 2016 > 39 > 8 > 516-526

Lactobacillus kunkeei is classified as a sole obligate fructophilic lactic acid bacterium that is found in fructose-rich niches, including the guts of honeybees. The species is differentiated from other lactobacilli based on its poor growth with glucose, enhanced growth in the presence of oxygen and other electron acceptors, and production of high concentrations of acetate from the metabolism of glucose...

article

Probiotics modulate gut microbiota and health status in Japanese cedar pollinosis patients during the pollen season

Gaku Harata, Himanshu Kumar, Fang He, Kenji Miyazawa, more

European Journal of Nutrition > 2017 > 56 > 7 > 2245-2253

Background Japanese cedar pollinosis (JCP) is a challenging public health problem in Japan. Altered gut microbiota is associated with several diseases, including allergic diseases. However, only a few studies have focused on JCP and the underlying mechanisms for probiotic effects remain unclear. In addition, this study is the first observation of the correlation between the gut microbiota and blood...

chapter

Probiotics and Allergy

Seppo Salminen, Erika Isolauri

Prebiotics and Probiotics Science and Technology > 977-995

The atopic diseases include atopic eczema, allergic rhinitis and asthma. The prevalence of atopic diseases has been on the rise for several decades, particularly in high-income industrialized nations (ISAAC, 1998; Sibbald et al., 1990). As potential explanations for the increased prevalence of atopic diseases the so-called hygiene hypothesis has been suggested. The hypothesis suggests that the continuously...

article

Allergy Associations with the Adult Fecal Microbiota: Cause, Effect or Biomarker?

Seppo Salminen

EBioMedicine > 2016 > 3 > Complete > 15-16

article

Furry pets modulate gut microbiota composition in infants at risk for allergic disease

Merja Nermes, Akihito Endo, Jasmin Aarnio, Seppo Salminen, more

Journal of Allergy and Clinical Immunology > 2015 > 136 > 6 > 1688-1690.e1

article

Gut Bifidobacterium microbiota in one-month-old Brazilian newborns

Łukasz Grześkowiak, Tatiana Fiche Sales Teixeira, Solange Mara Bigonha, Guilherme Lobo, more

Anaerobe > 2015 > 35 > Part B > 54-58

Gut colonisation with bifidobacteria in early infancy is essential for the well-being of the infant. Gestational age and mode of delivery are among the factors influencing the colonisation process. The aim was to characterise the bifidobacterial composition in the gut of one-month-old full-term and pre-term Brazilian infants, both being delivered vaginally or by caesarean section. Fourty nine Brazilian...

article

Microbiota and probiotics in canine and feline welfare

Łukasz Grześkowiak, Akihito Endo, Shea Beasley, Seppo Salminen

Anaerobe > 2015 > 34 > Complete > 14-23

Dogs and cats have been cohabiting with us for thousands of years. They are the major human companions. Today, dogs and cats live in urban areas. Cats and most dogs are on high carbohydrate diets and face similar life-style challenges as the human beings. The health and well-being of companion animals, just as their owners, depends on the gut microbes. Providing a proper care and nutritionally balanced...

article

Novel probiotics and prebiotics: road to the market

Himanshu Kumar, Seppo Salminen, Hans Verhagen, Ian Rowland, more

Current Opinion in Biotechnology > 2015 > 32 > C > 99-103

Novel probiotics and prebiotics designed to manipulate the gut microbiota for improving health outcomes are in demand as the importance of the gut microbiota in human health is revealed. The regulations governing introduction of novel probiotics and prebiotics vary by geographical region. Novel foods and foods with health claims fall under specific regulations in several countries. The paper reviews...

article

Impact of orally administered lozenges with Lactobacillus rhamnosus GG and Bifidobacterium animalis subsp. lactis BB-12 on the number of salivary mutans streptococci, amount of plaque, gingival inflammation and the oral microbiome in healthy adults

Aino Toiviainen, Heli Jalasvuori, Emilia Lahti, Ulvi Gursoy, more

Clinical Oral Investigations > 2015 > 19 > 1 > 77-83

Objectives The aim was to evaluate the effects of orally administered Lactobacillus rhamnosus GG (LGG) and Bifidobacterium animalis subsp. lactis BB-12 (BB-12) on the number of salivary mutans streptococci (MS), amount of plaque, gingival inflammation and the oral microbiota in healthy young adults. Materials and methods The study was a randomised, controlled, double-blind trial. Healthy volunteers...

article

The gut microbiota and inflammatory noncommunicable diseases: Associations and potentials for gut microbiota therapies

Charles MacKay, Seppo Salminen, Gary Wong, John Sinn, more

The Journal of Allergy and Clinical Immunology > 2015 > 135 > 1 > 3-13

article

Long-term monitoring of the human intestinal microbiota from the 2nd week to 13 years of age

Akihito Endo, Anna Pӓrtty, Marko Kalliomӓki, Erika Isolauri, more

Anaerobe > 2014 > 28 > Complete > 149-156

Microbial contact begins prior to birth and continues rapidly thereafter. Few long term follow-up studies have been reported and we therefore characterized the development of intestinal microbiota of ten subjects from the 2nd week of life to 13 years of age. PCR-denaturing gradient gel electrophoresis combined with several bacterial group-specific primer sets demonstrated the colonization steps of...

article

Polyamine supplementation in infant formula: Influence on lymphocyte populations and immune system-related gene expression in a Balb/cOlaHsd mouse model

Carlos Gómez-Gallego, Rafael Frias, Gaspar Pérez-Martínez, María José Bernal, more

Food Research International > 2014 > 59 > Complete > 8-15

The aim of this work was to study whether the proportion of polyamine found in human milk, administered with a commercial infant formula, affected the maturation of the immune system in a BALB/cOlaHsd mouse model. Forty-eight pups (14-days old) were randomly assigned to four-day intervention groups: 1) breast-fed (normal lactation); 2) fed infant formula; and 3) two different groups fed with infant...

article

Food matrices and cell conditions influence survival of Lactobacillus rhamnosus GG under heat stresses and during storage

Akihito Endo, Johanna Teräsjärvi, Seppo Salminen

International Journal of Food Microbiology > 2014 > 174 > Complete > 110-112

The present study evaluated impact of moisture content and cell conditions on survival of probiotic strain, Lactobacillus rhamnosus GG, under lethal heat stresses and during long-term storage using freeze-dried cells and oils as matrices. Viable cell counts of freeze-dried L. rhamnosus GG cells suspended in oils had only 1-log-reduction after 5min at 80°C and approximately 3-log-reduction after 20min,...

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INFONA - science communication portal

Search results for: Seppo Salminen

The ability of human intestinal anaerobes to metabolize different oligosaccharides: Novel means for microbiota modulation?

The impact of probiotic supplementation during pregnancy on DNA methylation of obesity-related genes in mothers and their children

Proceedings of the 2017 WAO Symposium on Hot Topics in Allergy: Pediatric & Regulatory Aspects

Correlation between in vitro and in vivo assays in selection of probiotics from traditional species of bacteria

Long‐term safety and efficacy of perinatal probiotic intervention: Evidence from a follow‐up study of four randomized, double‐blind, placebo‐controlled trials

A canine-specific probiotic product in treating acute or intermittent diarrhea in dogs: A double-blind placebo-controlled efficacy study

The human milk microbiome and factors influencing its composition and activity

Genomic characterization of a fructophilic bee symbiont Lactobacillus kunkeei reveals its niche-specific adaptation

Probiotics modulate gut microbiota and health status in Japanese cedar pollinosis patients during the pollen season

Probiotics and Allergy

Allergy Associations with the Adult Fecal Microbiota: Cause, Effect or Biomarker?

Furry pets modulate gut microbiota composition in infants at risk for allergic disease

Gut Bifidobacterium microbiota in one-month-old Brazilian newborns

Microbiota and probiotics in canine and feline welfare

Novel probiotics and prebiotics: road to the market

Impact of orally administered lozenges with Lactobacillus rhamnosus GG and Bifidobacterium animalis subsp. lactis BB-12 on the number of salivary mutans streptococci, amount of plaque, gingival inflammation and the oral microbiome in healthy adults

The gut microbiota and inflammatory noncommunicable diseases: Associations and potentials for gut microbiota therapies

Long-term monitoring of the human intestinal microbiota from the 2nd week to 13 years of age

Polyamine supplementation in infant formula: Influence on lymphocyte populations and immune system-related gene expression in a Balb/cOlaHsd mouse model

Food matrices and cell conditions influence survival of Lactobacillus rhamnosus GG under heat stresses and during storage

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