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Background: The single nucleotide polymorphism SNP309 with a change from T to G in the promoter region of the MDM2 gene is shown to increase the MDM2 protein levels and attenuate the p53 levels and associates with disease progression in several tumors.
Objective: In this study, the role of the polymorphism was investigated with regard to the clinical outcome in B‐cell chronic lymphocytic leukemia...
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