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The differentiation of intoxication courses is one of the most difficult challenges for forensic pathologists and toxicologists. The case of a 52-year-old female inpatient of a psychiatric clinic with multiple medications who died from doxepin intoxication is reported. Concentrations of doxepin metabolites and isomers, pharmacokinetic modelling and genotyping of the doxepin-metabolizing cytochrome...
Die differenzierte Betrachtung und Rekonstruktion von Intoxikationsverläufen stellt Rechtsmediziner und forensische Toxikologen nicht selten vor große Herausforderungen. Im vorliegenden Beitrag wird die Kasuistik der 52 Jahre alt gewordenen Patientin einer psychiatrischen Klinik unter Mehrfachmedikation berichtet, die nachts im Bett liegend verstorben war. Konzentrationen von Doxepinmetaboliten und...
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