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The cell adhesive motif RGD tripeptide was synthesized by using a novel chemical method. First, Gly-Asp(GD) was synthesized in two steps including the chloroacetylation of free L-aspartic acid and the ammonolysis of the chloro-acetylated L-aspartic acid. The yield of chloroacetylated L-aspartic acid was 83. 0%. For the ammonolysis of chloro-acetylated L-aspartic acid, the yield of the ammonolyzed...
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