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Neben den natürlichen regulatorischen T-Zellen (Tregs) aus dem Thymus sind eine Vielzahl peripher induzierter Tregs von zentraler Bedeutung für die Immunhomöostase. Durch homotypische Wechselwirkungen zwischen aktivierten Effektor-T-Zellen und ruhenden Gedächtnis-T-Zellen konnten in vitro Tregs induziert werden, die sowohl Interleukin-10 als auch Interferon-γ produzieren. Dieser Mechanismus in der...
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