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NO66 is a JmjC domain‐containing histone demethylase with specificity towards histone H3 methylated on both Lys4 and Lys36 in vitro and in vivo. A fragment of NO66 lacking the N‐terminal 167 amino‐acid residues was overexpressed in Escherichia coli, purified and crystallized using the sitting‐drop vapour‐diffusion method. X‐ray diffraction data were collected to a resolution of 2.29 Å. NO66 crystallized...
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