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Viral inhibition by double-stranded (ds)RNA is a potential therapeutic approach for controlling shrimp viral diseases. Here, we describe the successful oral application of dsRNA targeting Laem-Singh Virus (LSNV) to diminish monodon slow growth syndrome (MSGS) in Thai Penaeus monodon. Shrimp feed formulated with bacterially expressed LSNV-dsRNA was given to shrimp for 9 weeks. RT-PCR results revealed...
Monodon slow-growth syndrome (MSGS) is a condition of Penaeus monodon cultivation ponds characterized by abnormally slow growth and coefficients of size variation greater than 35%. Shrimp from these ponds often show the presence Laem-Singh virus (LSNV) in the lymphoid organ, heart and other tissues. We compared various tissues of abnormally small and normal size (large) P. monodon from 3 MSGS ponds...
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