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The matrix metalloproteinases, tissue inhibitors of metalloproteinases and angiogenesis contribute to growth and spread of cancer. We investigated the correlation between pretreatment serum levels of tissue inhibitor of metalloproteinase 1 (TIMP-1) and vascular endothelial growth factor A (VEGF-A), and clinicopathologic features and survival in patients with esophageal cancer (EC). Serum TIMP-1...
It has been suggested that interleukin 6 (IL‐6) plays a potential role in the growth and progression of tumors, including esophageal cancer (EC). The aim of the study was to compare clinical significance of serum IL‐6 with classic tumor markers – carcinoembryonic antigen (CEA) and squamous cell cancer antigen (SCC‐Ag) – in EC patients in relation to its histological types – squamous cell carcinoma...
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