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Twenty‐one novel 5‐phenyl‐1,3,4‐oxadiazole‐2‐thiol (POT) substituted N‐hydroxyethyl quaternary ammonium salts (6a–g, 7a–g, 8a–g) were prepared and characterized by FTIR, NMR, and elemental analysis. Compounds 6a, 6c, and 8a were confirmed by X‐ray single‐crystal diffraction. They display the unsurpassed antibacterial activity against Staphylococcus aureus, α‐H‐tococcus, Escherichia coli, P. aeruginosa...
Five N‐methyl‐N‐R‐N,N‐bis(2‐hydroxyethyl) ammonium bromides (R = ‐benzyl (chloride, BNQAS), ‐dodecyl (C12QAS), ‐tetradecyl (C14QAS), ‐hexadecyl (C16QAS), ‐octadecyl (C18QAS)) were prepared based on N‐methyldiethanolamine (MDEA) and halohydrocarbon. Five QAS were characterized by FTIR, NMR, and MS. BNQAS, C12QAS, C14QAS, and C16QAS were confirmed by X‐ray single‐crystal diffraction. Their antibacterial...
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