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The effects of cisplatin (cisdiamminedichloroplatinum II) at the concentration of 20 µM
and transplatin (transdiamminedichloroplatinum II) at the concentrations of 20 µM and 200 and transplatin at the concentration of 200 µM were found to cause a significant increase of
thiobarbituric add reactive substances (TBARS).
We have demonstrated, that cisplatin - induced platelet lipid peroxidation was...
Badano metabolizm natywnych i metylowanych cząsteczek LDL w osoczu królika.
Chemiczna modyfikacja (reduktywna metylacja) reszt lizynowych w apoproteinie
pozwala na określenie in vivo przemiany LDL zależnej i niezależnej
ód specyficznych receptorów.
Badano wpływ promieniowania ultrafioletowego (UV-A, 360 nm) na zachowanie
się w płytkach krwi wolnych grup sulfhydrylowych szybko reagujących z DTNB.
Wykazano, że poziom grup -SH gwałtownie wzrasta w napromienionych płytkach (15, 30, 60 min, UV-A, 0,5 W/cm 9). Wzrost ten jest tylko w nieznacznym
stopniu zależny od grup -SH związanych z materiałem uwalnianym z płytek.
In avian thtorabocytes, like in mammalian blood plateleta the adenine nucleotides
are present in three distinguishable compartments. For studies of
adenine nucleotide metabolic pool the turkey thrombocytes were prelabeled with
3 H-adenine. The level of metabolic nucleotides' was follewed by measuring
their total radioactivity. Part of the metabolic adenine nucleotide pool was
not gextracted by...
P-selectin is stored in the a granules of blood platelets. Following platelet activation by
different agonists, P-selectin is expressed on the cell surface where it mediates adhesion
primarily to leucocytes.The aim of the study was to evaluate the direct effect of Proteus
mirabilis lipopolysaccharides on the P-selectin expression on the platelet surface measured by
cytometric method. The obtained...
The effects of two doses of UVB radiation (1.08 J/cm2 and 4.32 J/cm2; 1.2 mW/cm2) on
blood platelets secretion of adenine nucleotides and proteins and P selectin expression were
studied. The effect of UVB radiation on P selectin expression (marker of platelet activation)
was compared with the effect of thrombin, which is a strong platelet agonist. The obtained
results showed that exposure of blood...
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