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Two alternative approaches to medicinal plant transcriptome analysis, RNA sequencing (RNA‐seq) and digital gene expression (DGE), are sequence based and have become increasingly popular due to rapid developments in high‐throughput sequencing technologies. Among the high‐throughput sequencing techniques, the 454 pyrosequencing and Illumina sequencing platforms are the first to be commercially available...
CPUY11018 has anti‐atrial fibrillation (AF) effects in rats. The effects of CPUY11018 on the transient outward K+ current (Ito) and ultra‐rapid delayed rectifier K+ current (IKur) were studied using whole‐cell patch clamp techniques and an acetylcholine (ACh)‐CaCl2 induced AF model. CPUY11018 inhibited Ito and IKur in a concentration‐dependent manner with IC50 values of 18.5 and 1.7 µM, respectively...
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