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Cyclosporin A (CsA) is known to decrease nitric oxide (NO) release in the nervous system. The present study was aimed at investigating the effects of acute administration of CsA on pentylenetetrazole (PTZ)-induced seizure threshold and latency and probable modulation of these effects by NO synthesis substrate l-arginine, and NO synthesis inhibitors N G -nitro-l-arginine methyl ester (l-NAME)...
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