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ObjectivesInterleukin (IL)‐33 is a novel member of pro‐inflammatory cytokine IL‐1 family, which plays an important role in the immune response. IL‐33 was proved to involve in many inflammatory and allergic diseases, thus the inhibition of this cytokine may be a promising treatment for these diseases. Arms of the study were to generate mouse soluble IL‐33 receptor fused with human IgG1 Fc domain (msIL33R‐Fc)...
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