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Blood platelets when activated are involved in the mechanisms of hemostasis and thrombosis, and their migration toward injured vascular endothelium necessitates interaction with red blood cells (RBCs). Rheology co-factors such as a high hematocrit and a high shear rate are known to promote platelet mass transport toward the vessel wall. Hemodynamic conditions promoting RBC aggregation may also favor...
Cardiopulmonary bypass (CPB) used during cardiac surgery induces a systemic inflammatory response. The severity of that response has been shown to be proportional to patient outcome. Markers of inflammation are typically obtained intermittently through blood testing with variable delay. Red blood cell (RBC) aggregation is a surrogate marker of inflammation that can be quantified with ultrasound. It...
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