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Background Anti-citrullinated protein antibodies (ACPA) are central to rheumatoid arthritis (RA) pathogenesis and may develop at inflamed mucosa. We investigated whether asthma, a disease of airway mucosal inflammation, was associated with elevated ACPA before RA diagnosis. Methods We performed a nested case-control study among women in two prospective cohorts, the Nurses’ Health Study (NHS; 1976–2014)...
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